National Heart Month: cardiologists discover the cause of a fluttering heartbeat

Researchers from the University of British Columbia in Canada have revealed that the beating of heart cells is controlled by sodium and calcium ions moving through the cells. It is thought that this discovery can reveal the cause and new treatment targets for cardiac arrhythmia.

A heart beat is controlled by atoms of sodium, potassium and calcium passing through molecular channels between the heart cells; if these channels malfunction or leak it will lead to an irregular heartbeat or heart rhythm disorder. The scientists found that the molecular channels are highly complex and have an associated role with proteins to prevent the channels from being blocked and to control the flow of atoms into the heart. A lack of sodium, or too much sodium, reaching the cells is caused by a genetic mutation and leads to two types of arrhythmia: Brugada Syndrome and Long Q-T type 3.

Treatments for heart rhythm disorders include catheter ablation and a new treatment called laser balloon ablation. For more information on heart arrhythmias please click here.

Any form of disturbance to the heart's normal regular beat Full medical glossary
The smallest units of an element. Full medical glossary
The two upper chambers of the heart. Full medical glossary
An element that forms the structure of bones and teeth and is essential to many of the body's functions. Full medical glossary
Relating to the heart Full medical glossary
A tube used either to drain fluid from the body or to introduce fluid into the body. Full medical glossary
a treatment for atrial fibrillation using catheters inside the heart to ablate tissue using a laser guided by a camera. Full medical glossary
The basic unit of all living organisms. Full medical glossary
Abnormally fast and uneven contractions of the heart muscle, so that blood cannot be pumped efficiently Full medical glossary
The basic unit of genetic material carried on chromosomes. Full medical glossary
Relating to the genes, the basic units of genetic material. Full medical glossary
A large abdominal organ that has many important roles including the production of bile and clotting factors, detoxification, and the metabolism of proteins, carbohydrates and fats. Full medical glossary
A change in the genetic material (DNA) of a cell, or the change this this causes in a characteristic of the individual, which is not caused by normal genetic processes. Full medical glossary
An element that is one of the main ions, or charged atoms, of intracellular fluid, and is also important in nerve and muscle function. Full medical glossary
Compounds that form the structure of muscles and other tissues in the body, as well as comprising enzymes and hormones. Full medical glossary
One of the chemical components of salt (sodium chloride) and an important blood chemical. Full medical glossary