Is Vitamin D a hormone?

It is probably fair to say that most people would consider Vitamin D to be nutrient that acts as a bone health vitamin. However, according to the medical literature including PubMed, "Vitamin D, a secosteroid (pro)-hormone, has been traditionally considered as a key regulator of bone metabolism, and calcium and phosphorous homeostasis through a negative feedback with the parathyroid hormone". However, they go onto say that during the last twenty years, the role played by vitamin D has been largely revised by recognising it a "pleiotropic" (i.e. affecting multiple body parts) action on a wide spectrum of systems, apparati, and tissues. Thus, vitamin D has growingly been involved as the key influencing factor of biological modifications and specific clinical conditions.

Your body makes vitamin D from cholesterol (in the presence of sunlight)

Making vitamin DDr Doug Corrigan explains it in a far more straightforward fashion, he says that vitamin D is, "a steroid hormone precursor that your body synthesises from cholesterol when your skin is exposed to UVB rays from sunlight".

Dr Corrigan Ph.D. ia s Biochemist & Molecular Biologist, Physicist, Award Winning Global Super Solver is also the author of;

The Author of Light: Did God Reveal His Identity in the Physics of Light

To become fully activated, the steroid hormone precursor must also be processed by your liver and activated becomes a substance known as 'calcitriol'. Once activated, Vitamin D binds to Vitamin D Receptors (VDRs) found in nearly every cell in your body. This binding causes modulation of the expression of over 200 genes involved in:

  • Immune regulation
  • Cell growth and repair
  • Calcium and phosphate balance, and
  • Inflammation modulation

This list underpins the importance of the 'steroid hormone precursor' and its role in immunity against viral infections, and normal, healthy body function. Vitamin D enhances innate immunity while preventing overactive inflammatory responses, which is critical for fighting infections without triggering chronic inflammation.

Vitamin D helps your gut absorb calcium efficiently, preventing osteoporosis. Low Vitamin D levels are associated with mood disorders and cognitive decline in observational studies, likely due to its role in neuroimmune pathways.

Deficiency is common, especially if you live in extreme latitudes, spend most of your time indoors, or have darker skin (which reduces Vitamin D synthesis).

Blood levels are best assessed as 25(OH)D (calcidiol). Levels above 30 ng/mL for optimal health, though ideal ranges can vary.

How do you optimise your Vitamin D levels?

Aim for moderate sun exposure.

Include fatty fish and egg yolks in your diet.

Take a Vitamin D3 supplement.

An element that forms the structure of bones and teeth and is essential to many of the body's functions. Full medical glossary
The basic unit of all living organisms. Full medical glossary
A substance present in many tissues and an important constituent of cell membranes although high concentrations of a certain type of cholesterol in the blood are unhealthy. Full medical glossary
A disease of long duration generally involving slow changes. Full medical glossary
One of the three main food constituents (with carbohydrate and protein), and the main form in which energy is stored in the body. Full medical glossary
A viral infection affecting the respiratory system. Full medical glossary
The basic unit of genetic material carried on chromosomes. Full medical glossary
A substance produced by a gland in one part of the body and carried by the blood to the organs or tissues where it has an effect. Full medical glossary
Invasion by organisms that may be harmful, for example bacteria or parasites. Full medical glossary
The body’s response to injury. Full medical glossary
A large abdominal organ that has many important roles including the production of bile and clotting factors, detoxification, and the metabolism of proteins, carbohydrates and fats. Full medical glossary
The chemical reactions necessary to sustain life. Full medical glossary
A condition resulting in brittle bones due to loss of bony tissue. Full medical glossary
A gland in the neck that produces hormones with a role in controlling metabolism. Full medical glossary
A group of cells with a similar structure and a specialised function. Full medical glossary
Essential substances that cannot be produced by the body and so must be acquired from the diet. Full medical glossary