The Effective Treatment of Osteoporosis with Oestrogen Hormone

Effective treatment of Osteoporosis with Oestrogen

Professor John Studd

Editor's foreword

Professor John Studd is generally regarded as the leading light in the campaign for women’s medicine and healthcare. He was awarded the Gold Medal of the Royal Society of Medicine for the obstetrician/gynaecologist who has made the greatest lifetime contribution to women's health. He has fought the medical cause on behalf of women and has been proved consistently correct in his views on the important role of hormone therapy. He says that both doctors and patients need to be aware that HRT should be the frontline treatment and that women are best cared for by the appropriate experts i.e. gynaecologists. Oestrogen is proved to be the best treatment to prevent the symptoms of menopause, not to mention the horror of spine fractures associated with osteoporosis. In the meantime big pharma has stepped in to fill the treatment void caused by the discredited 2002 WHI Study with their own alternative products such as the bisphophonates and antidepressants (see - Profox nightmare) and the danger is that these drugs can do more harm than good.

The Royal College of Obstetricians and Gyneacologists website states:

“The effects of HRT have been studied in over a million women worldwide and research shows that for most women HRT works and is safe.”

 

Why Women can now Benefit from Oestrogen Treatment

“Hormone therapy is the most logical and the most beneficial treatment for low bone density”.

 

HRT - Altered Opinions

About 20 years ago Hormone Replacement Therapy (HRT) was the only really effective treatment for osteoporosis. However, following the bad news fallout from the 2002 WHI study, oestrogens were subsequently considered not to be the first choice of therapy. Fortunately for women this study has now been totally discredited and retracted even by the investigators. As a result of the WHI study most physicians who are virtually always poorly trained in hormone therapy happily resorted to the use of bisphosphonates, strontium, parathyroid hormone or worse.  These treatments may be appropriate for the older patient but for the younger woman on long term therapy there are major side effects including epigastric pain, osteonecrosis of the jaw, femoral mid-shaft fractures and there is also a suggestion of an increase in oesophageal cancer.

The evidence is now clear that the safest and most effective way to increase bone density in women under the age of 60 years is by treatment with oestrogen.  The denial of oestrogen to these younger women is tragic when we consider the many younger 30-40 year old women with premature menopause or with a history of anorexia and amenorrhea.

Thin Women Deficient in Oestrogen

Thin women including those with an exercise and / or marathon running addiction, or healthy thin women who consider walking the dog for 2 hours a day sufficient exercise may also be deficient in oestrogen.  For these women, the oestrogen deficiency could be due to premature ovarian failure or amenorrhea or simply because they are thin and not producing sufficient oestradiol in their own body fat. In these cases transdermal oestrogen must be regarded as the correct first choice of treatment.  Similarly premenopausal women are at risk if they have a hysterectomy and bilateral oophorectomy without appropriate hormone replacement. These women clearly need oestrogen to treat the post oophorectomy symptoms as well as for protection of the skeleton.

Oestrogen Treatment Anabolic for Skin and Spine

There is a decrease in skin collagen sssociated with ovarian failure regardless of age due to lack of oestrogen. Oestrogen therapy will replace the missing hormone and improve the quality of skin thickness and skin elasticity.  Equally the loss of collagen also happens in the bone matrix, which is the vital scaffolding and structure of the bone.  Oestrogen replaces the missing collagen in the matrix of osteopenic bone. This same anabolic effect upon the collagen protects the intervertebral discs in the spine. The discs make up one quarter of the length of the spinal column and serve as a cushion protecting your spine and preventing the development of vertebral crush fractures. This is why osteopenia or, of course, osteoporosis are major causes of spine fractures. Oestrogens protect the intervertebral discs and bisphosphonates do not.

A Generation to dispel the old HRT Myths

“The most beneficial treatment for low bone density”

Any anxiety about the safety of HRT should have disappeared by now. However, a major problem remains in that the spurious ‘side effect’ of HRT in women is now in the undergraduate textbooks and it will take a generation to get rid of this misinformation.  Women may also have regular or even troublesome periods or may develop breast discomfort on HRT.  These are relatively minor problems that a gynaecologist can deal with. The problem is that these symptoms are outside of the training of bone physicians and so these doctors will continue to be reluctant to use the most logical and the most beneficial treatment for low bone density.

All the latest information indicates that HRT is safe and is associated with the removal of most of the climacteric symptoms including loss of libido and depression as well as the more obvious hot flushes and sweats. 

Oestrogen Implants Preferred

It is safer to use transdermal oestrogens as this route does not stimulate coagulation factors from the liver and does not encourage deep vein thrombosis (DVT), stroke or pulmonary emboli. It does seem that the risk factor in HRT is more with the cyclical or continuous progestogen.  Following hysterectomy women can have oestrogens probably with the addition of testosterone without progestogen and data now from two large studies confirm that this is associated with less breast cancer and fewer heart attacks and cardiac deaths.

Women should not be denied this effective treatment

There seems no reason to deny women particularly under the age of 50 years relief of symptoms and protection of osteoporosis by denying them the transdermal oestrogen treatment.  It seems that this is an important lesson that many physicians have yet to learn.

A loss of appetite resulting in weight loss. Anorexia nervosa is a psychological illness in which self-starvation leads to weight loss. Full medical glossary
On both sides of the body Full medical glossary
A class of drugs used in osteoporosis and other bone diseases to reduce loss of bone mass Full medical glossary
Abnormal, uncontrolled cell division resulting in a malignant tumour that may invade surrounding tissues or spread to distant parts of the body. Full medical glossary
Relating to the heart Full medical glossary
A substance that can undergo a cascade of reactions in certain conditions, leading to the coagulation of blood. Also known as clotting factor. Full medical glossary
A group of substances that can undergo a cascade of reactions in certain conditions, leading to the coagulation of blood. Also known as clotting factors. Full medical glossary
Obstruction of one of the deep veins, often in the calf, by a blood clot. Often abbreviated to DVT. Full medical glossary
Feelings of sadness, hopelessness and a loss of interest in life, combined with a sense of reduced emotional well-being Full medical glossary
An abbreviation for deep vein thrombosis: the obstruction of one of the deep veins, often in the calf, by a blood clot. Full medical glossary
One of the three main food constituents (with carbohydrate and protein), and the main form in which energy is stored in the body. Full medical glossary
Relating to the area at the top of the thigh, near the top of the femur (thigh bone). Full medical glossary
A viral infection affecting the respiratory system. Full medical glossary
The basic unit of genetic material carried on chromosomes. Full medical glossary
The death of a section of heart muscle caused by an interruption in its blood supply. Also called a myocardial infarction. Full medical glossary
A substance produced by a gland in one part of the body and carried by the blood to the organs or tissues where it has an effect. Full medical glossary
Abbreviation for hormone replacement therapy, the administration of female hormones in cases where they are not sufficiently produced by the body. Full medical glossary
The surgical removal of the uterus (womb). Full medical glossary
One of the tough pads of fibre and cartilage that separate the vertebrae and act as cushions to absorb forces on the spine. Full medical glossary
Sexual drive. Full medical glossary
A large abdominal organ that has many important roles including the production of bile and clotting factors, detoxification, and the metabolism of proteins, carbohydrates and fats. Full medical glossary
Relating to the menopause, the time of a woman’s life when her ovaries stop releasing an egg (ovum) on a monthly cycle. Full medical glossary

The time of a woman’s life when her ovaries stop releasing an egg (ovum) on a monthly cycle, and her periods cease

Full medical glossary
Death of cells or tissue in the body due to disease, injury or impaired blood supply. Full medical glossary
The main female hormone. Full medical glossary
A hormone involved in female sexual development, produced by the ovaries. Full medical glossary

A  condition in which the protein and mineral content of bone tissue is reduced, but less severely than in osteoporosis.

Full medical glossary
A condition resulting in brittle bones due to loss of bony tissue. Full medical glossary
relating to the ovaries Full medical glossary
A tube placed inside a tubular structure in the body, to keep it patent, that is, open. Full medical glossary
Any sudden neurological problem caused by a bleed or a clot in a blood vessel. Full medical glossary
The main male sex hormone. Full medical glossary
The formation of a blood clot. Full medical glossary
A gland in the neck that produces hormones with a role in controlling metabolism. Full medical glossary
A blood vessel that carries blood towards the heart. Full medical glossary
Affecting the vertebrae, the bones of the spine, or the joints between them Full medical glossary
ventricular tachycardia Full medical glossary