Identifying the Genetics of Alzheimer’s Disease

Research conducted by Cardiff University has led to the discovery of five new genes linked to Alzheimer’s disease doubling the number of genes known to be linked to this disease.

The genes affect three bodily processes, the way the body deals with fat and cholesterol, the mechanism by which brain cells process molecules and the immune system

If the effects of all 10 of these genes could be eradicated the risk of developing the disease could be cut by 60%. Alzheimer’s disease is thought to be between 60 and 79% genetic with lifestyle and the environment presenting the other risks. 

Currently 500,000 people within the UK suffer from Alzheimer’s disease, and with an increasingly ageing population a major concern, it is estimated that by 2021 dementia may affect up to 1 million people. 

The basic unit of all living organisms. Full medical glossary
A substance present in many tissues and an important constituent of cell membranes although high concentrations of a certain type of cholesterol in the blood are unhealthy. Full medical glossary
Decline in mental capacity, brain functioning and memory that affects day-to-day living. Full medical glossary
One of the three main food constituents (with carbohydrate and protein), and the main form in which energy is stored in the body. Full medical glossary
The basic unit of genetic material carried on chromosomes. Full medical glossary
Relating to the genes, the basic units of genetic material. Full medical glossary
The organs specialised to fight infection. Full medical glossary
An element present in haemoglobin in the red cells. Full medical glossary