Total Health's blog

Enter the P4 Health Revolution

Most health delivery systems around the globe such as the NHS are not infact based on health, most people do not enter a health system unless they are sick. It is therefore argued with some justification that a paradigm shift is required to turn the emphasis one hunded and eighty degrees, and that P4 Medicine Bioinformatics is the required technology driver to bring about this change.

London Cancer Genetics Expert

There are major implications when looking for a faulty geneThe basic unit of genetic material carried on chromosomes. that may run in the family. The relatives of people who have had cancerAbnormal, uncontrolled cell division resulting in a malignant tumour that may invade surrounding tissues or spread to distant parts of the body. may wish to be tested to see if they too carry the gene, especially the daughters of women who have had breast or ovarianrelating to the ovaries cancer. However, prior to being tested, it is important to discuss the pros and cons because geneticRelating to the genes, the basic units of genetic material. testing does not necessarily bring certainty, but does bring alot more information - mostly 'probability-type' information.

Genetic testing and biomarkers for Cancer

Finding new and significant biomarkersA substance that can be measured to help healthcare professionals to assess normal processes, disease processes or a person's response to treatment. in a patient's DNAThe building blocks of the genes in almost all living organisms - spelt out in full as deoxyribonucleic acid. is being widely reported as the future of diagnostic-led medicine. The theory is that by knowing a patient's genome, finding the presence of mutations and knowing how these mutations affect the effectiveness of different treatment options means that every patient will potentially be able to receive personalised treatment regimes.DNA sequencing

Google Diagnostics

Combining Medical Diagnostics and Pathology with Datasets

The term 'diagnostics' applies equally to the medical as well as the technology settings, however, the two settings are now being merged with the application of mHealth.

Ovarian cancer linked to Lynch Syndrome

The most common form of ovarianrelating to the ovaries cancerAbnormal, uncontrolled cell division resulting in a malignant tumour that may invade surrounding tissues or spread to distant parts of the body. is called 'high grade serous cancer'. One in ten women with this form of cancer carry a geneThe basic unit of genetic material carried on chromosomes. alteration. Alterations in the BRCA1 or BRCA2 genes can cause inherited predispositions to cancer and this is sometimes more prevalent within certain populations including people with Ashkenazi Jewish ancestry, who also have an increased risk of ovarian cancer.

Is mindfulness the new heart therapy?

The link between stressRelating to injury or concern. and heart disease is a medical axiom. It would therefore appear to make perfect sense to tackle disease prevention at the stress management and psychological level i.e. healthy in mind, healthy in body. Dispositional Mindfulness

Cryoablation for Kidney Cancer

Ice and Cryoablation for Kidney Tumours

The beauty of using ice to destroy tumours is that it shows clearly on the CTThe abbreviation for computed tomography, a scan that generates a series of cross-sectional x-ray images scanner. This means that the interventional oncologistA specialist in the treatment of cancer., when performing tumour ablation can clearly see the impact of the treatment - and guide / contain this tissueA group of cells with a similar structure and a specialised function. destruction only to the tumour. The good news for the patient is that surgical radical jnephrectomy is no longer necessary meaning that renalRelating to the kidney. function can be preserved.

Rapid diagnosis of sepsis (blood poisoning)

Bugs can often get into the bloodA fluid that transports oxygen and other substances through the body, made up of blood cells suspended in a liquid. from either simple grazes or from brushing your teeth, but this does not normally cause sepsisInfection of a wound or body tissue with bacteria that leads to the formation of pus or to the multiplication of bacteria in the blood. . When bacteriaA group of organisms too small to be seen with the naked eye, which are usually made up of just a single cell. or virusesMicrobes that are only able to multiply within living cells. get into the blood most people's immune systems rapidly and appropriately respond to the presence of these minor invasions. Depending on the type of bacteria these bugs are normally quickly and naturally dealt with, or there might be what is known as a 'mild sepsis'.

Are you ready for Mobile Health (mHealth)?

At what point will having 'a doctor in your pocket' become a reality? According to both Google and Apple the answer would appear to be 'pretty soon', afterall, healthcare is one of the last sectors to be affected by the information and technological revolution. Why is this? The main factor has been that there is a widely held belief that healthcare and medicine should be personal.

How safe is my drug?

The European Medicine Agency (EMA) have produced a new website to provide all patients and healthcare professionals with immediate access to information on reported suspected side-effects for over 1700 licensed medicines.Furthermore, the new website allows patients and doctors to report adverse events themselves - directly.

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