Patients who have recently been diagnosed with uterine fibroidsBenign tumours, most often in the uterus., or who have suffered from fibroids in the past are being asked to get involved by providing their thoughts and attitudes towards the condition, for the benefit of other women.
The type of breast cancerAbnormal, uncontrolled cell division resulting in a malignant tumour that may invade surrounding tissues or spread to distant parts of the body. a patient has determines the way in which the cancer is likely to behave or might metastasise to other parts of the body. The types of breast cancer are largely now defined according to their histology and size as well as now to the presence or absence of geneThe basic unit of genetic material carried on chromosomes. mutations (see chart below).
According to a review of health literacy levels in England carried out by Researchers from King's College Hospital and Keele University, health information available to the public, including patient information leaflets in GP surgeries are too complex for up to 61% of people.
Most health delivery systems around the globe such as the NHS are not infact based on health, most people do not enter a health system unless they are sick. It is therefore argued with some justification that a paradigm shift is required to turn the emphasis one hunded and eighty degrees, and that P4 Medicine Bioinformatics is the required technology driver to bring about this change.
There are major implications when looking for a faulty geneThe basic unit of genetic material carried on chromosomes. that may run in the family. The relatives of people who have had cancerAbnormal, uncontrolled cell division resulting in a malignant tumour that may invade surrounding tissues or spread to distant parts of the body. may wish to be tested to see if they too carry the gene, especially the daughters of women who have had breast or ovarianrelating to the ovaries cancer. However, prior to being tested, it is important to discuss the pros and cons because geneticRelating to the genes, the basic units of genetic material. testing does not necessarily bring certainty, but does bring alot more information - mostly 'probability-type' information.
Finding new and significant biomarkersA substance that can be measured to help healthcare professionals to assess normal processes, disease processes or a person's response to treatment. in a patient's DNAThe building blocks of the genes in almost all living organisms - spelt out in full as deoxyribonucleic acid. is being widely reported as the future of diagnostic-led medicine. The theory is that by knowing a patient's genome, finding the presence of mutations and knowing how these mutations affect the effectiveness of different treatment options means that every patient will potentially be able to receive personalised treatment regimes.
The most common form of ovarianrelating to the ovariescancerAbnormal, uncontrolled cell division resulting in a malignant tumour that may invade surrounding tissues or spread to distant parts of the body. is called 'high grade serous cancer'. One in ten women with this form of cancer carry a geneThe basic unit of genetic material carried on chromosomes. alteration. Alterations in the BRCA1 or BRCA2 genes can cause inherited predispositions to cancer and this is sometimes more prevalent within certain populations including people with Ashkenazi Jewish ancestry, who also have an increased risk of ovarian cancer.
The link between stressRelating to injury or concern. and heart disease is a medical axiom. It would therefore appear to make perfect sense to tackle disease prevention at the stress management and psychological level i.e. healthy in mind, healthy in body.